TRANSCRIPT AND PROTEIN EXPRESSION PROFILE OF PF11_0394, A PLASMODIUM FALCIPARUM PROTEIN EXPRESSED IN SALIVARY GLAND SPOROZOITES

Transcript and protein expression profile of PF11_0394, a Plasmodium falciparum protein expressed in salivary gland sporozoites

Abstract Background Plasmodium falciparum malaria is a significant problem around the world today, thus there is still a need for new control methods to be developed.Because the sporozoite displays dual infectivity for both the mosquito salivary glands and vertebrate host tissue, it is a good target for vaccine development.Methods The P.falciparum

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A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer.

Molecular targeted therapies have been the focus of recent clinical trials for the treatment of patients with recurrent epithelial ovarian cancer (EOC).The majority have not fared well as monotherapies for improving survival of these patients.Poor bioavailability, lack of predictive biomarkers, and the presence of multiple survival pathways can all

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